おかしいな、スピーカーがガーガーいってるよ。

That's funny. The speaker is crackling.

どこかおかしいと一目で私にはわかりました。

I could tell at a glance that something was wrong.

君のジョークは何度聞いてもおかしい。

Your joke is funny no matter how many times I hear it.

洗濯機の調子がどこかおかしい。

Something is wrong with the washing machine.

君の基本的な理論はおかしいと思う。

I think your basic theory is wrong.

考えてみれば彼のいう事はおかしいよ。

Come to think of it, he is wrong.

私はもっと敵の抵抗があると踏んでたんだけど、むしろ中枢に進むほど敵が減ってきてる・・・。おかしいと思わないかしら？

I had expected stronger resistance from the enemy but if anything there are less of them as we advance to the centre... Don't you think that's strange?

あの老人は頭がおかしいにちがいない。

That old man must be off his rock.

「なに、アンタ疑ってんの」「だ、だってそんな、いきなり魔界とか魔族とか、信じろという方がおかしいよ」

"What? Are you doubting us?" "B-but, that is, suddenly 'spirit world', 'magical beings' - it's strange to ask me to believe."

人生は面白おかしい事ばかりではない。

Life is not all beer and skittles.

うむ。これだけのことをされて、ブチキレないほうがおかしい。

So. Having had all that done to him it would be stranger if he wasn't enraged.