setback; reverse; check; defeat; frustration; disappointment; to frustrate; to discourage; to set sb back; to blunt; to subdue

to thwart; to foil (sb's plans); a setback; a failure; a defeat

acne; pustule

frustration

thwarted; obstructed; setback

(of sales, prices etc) to fall; to drop; decline; slump

to win as a result of tenacious effort; to fight off tough competition

to frustrate; to inhibit; to make things difficult

devastating setback; slump (in stock market etc); crushing defeat; to cause a serious setback; to plummet